Difference between Dynamics CRM 2016 Online and On-Premise

Hi Dynamics CRM Team,

I am doing analysis of the Dynamics CRM for our development project. I tried to find the differences between the Online and On-premise application. Most of the documentation links refer the information beginning with 'Applies To: CRM 2016 on-prem, CRM Online'.

Is there any API difference between the Online and On-Premise 2016?

If at all any, could you please share the major differences and documentation for the same.

Regards,

Rajinder Singh